Myopathy

Myopathy is a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness. Myopathy means muscle disease (Greek : myo- muscle + patheia -pathy : suffering).
General signs and symptoms of myopathy include the following:
  • Symmetric proximal muscle weakness.
  • Malaise, fatigue.
  • Dark-colored urine (suggests myoglobinuria) and/or fever.
  • Absence of sensory complaints or paresthesias; however, deep tendon reflexes (DTRs) may be diminished/absent in hypokalemic paralysis.

The chronic inflammatory myopathies can‘t be cured in most adults but many of the symptoms can be treated. Options include medication, physical therapy, and rest. … The inflammatory myopathies are a group of diseases, with no known cause, that involve chronic muscle inflammation accompanied by muscle weakness.

There are many causes of muscle disease other than inflammation. They include infection, muscle injury due to medicine, inherited diseases that affect muscle function, disorders of electrolyte levels, and thyroid disease. It is unknown what causes inflammatory myopathies. … Inflammatory myopathies are rare.In the United States, Duchenne MD and Becker MD occur in approximately 1 in 3300 boys. Overall incidence of muscular dystrophy is about 63 per 1 million. Worldwide incidence of inflammatory myopathies (e.g., dermatomyositis, polymyositis) is about 5–10 per 100,000 people. These disorders are more common in women.Symptoms. In general, myopathy causes muscle weakness. The most common pattern of weakness is described as a proximal weakness. This means that the muscles of the upper arms and upper legs are more obviously weakened than the muscles of the hands or feet.